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Important Safety Information  |  Prescribing Information
Esperoct antihemophilic factor (recombinant), glycopegylated-exei logo.
Esperoct antihemophilic factor (recombinant), glycopegylated-exei logo.
Esperoct® is used to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Please see full indication and limitation below.
“Knowing that I can take Esperoct® with me is comforting.”
- Vaughn lives with hemophilia A and uses Esperoct®
Hemophilia A can sometimes make it difficult to live an active lifestyle, that’s why Vaughn chooses the flexibilitya and bleed protection offered by Esperoct®
“Going to Esperoct® was a pretty easy decision for me”  - Vaughn
 Learn more about Vaughn 
aPrior to reconstitution, Esperoct® can be stored from 36 °F to 46 °F for up to 30 months, at room temperature up to 86 °F for up to 12 months, or up to 104 °F for up to 3 months. See Prescribing Information for complete product storage information.
Meet Vaughn at NBDF, August 21, 2025 in Aurora, CO
Learn more
 
Keep scrolling to learn more
 
Selected Important Safety Information
Who should not use Esperoct®?
  • You should not use Esperoct® if you are allergic to factor VIII or any of the other ingredients of Esperoct® or if you are allergic to hamster proteins
What is the most important information I need to know about Esperoct®?
  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center
  • Call your healthcare provider right away or get emergency treatment right away if you get any signs of an allergic reaction, such as: hives, chest tightness, wheezing, dizziness, difficulty breathing, and/or swelling of the face
Please click here or scroll below for additional Important Safety Information.
 
Flexibility and bleed protection ON THE GO for ALL ages
Esperoct is the ONLY EHL product that can go with you from 86 °F to 104 °Fa
aPrior to reconstitution, Esperoct® can be stored from 36 °F to 46 °F for up to 30 months, at room temperature up to 86 °F for up to 12 months, or up to 104 °F for up to 3 months. See Prescribing Information for complete product storage information. Store reconstituted product in vial.
EHL=extended half-life
 
After reconstitution, Esperoct® can be:
  Used for up to
4 HOURS
 
  When stored at up to
86 °F
 
OR
 
  Used for up to
24 HOURS
 
  When stored in the refrigerator between
36 °F and 46 °F
 
“it’s huge to know that I can bring Esperoct® with me at up to 104 °F for up to 3 months”
- Vaughn lives with hemophilia A and uses Esperoct®
Plus Esperoct® comes in compact packaging for portability and is ready in 3 simple steps – for even more flexibility!
 
Are you comfortable trying Esperoct®?
Consider these questions before you choose a factor treatment:
• Will it control my bleeds?
• How often will you have to take a dose?
• Do you have to worry about storage temperature?
• How portable is it?
• How long will it take to prepare and infuse?
• What are the safety considerations?
You can find answers to all these questions, plus stories from Vaughn and others who treat their hemophilia A with Esperoct®
 Visit esperoct.com 
 
Looking for resources or people who understand the challenges you face?
There’s an entire community dedicated to supporting those living with hemophilia.
Connect with a Rare Blood Community Liaison (RBCL) to find local events, get personalized support, and learn more about Esperoct®.
 Find your RBCL 
 
What is Esperoct®?
Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] is an injectable medicine to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Esperoct® when you have surgery
  • Esperoct® is not used to treat von Willebrand Disease
Important Safety Information (cont’d)
What should I tell my healthcare provider before using Esperoct®?
  • Before taking Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII
  • Your body can make antibodies called “inhibitors” against Esperoct®, which may stop Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Esperoct®
What are the possible side effects of Esperoct®?
  • Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion
Please see Prescribing Information for Esperoct®.
Esperoct® is a prescription medication.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
PLEASE DO NOT RESPOND TO THIS EMAIL. If you would like to contact us, please click here or call 1‑877‑744‑2579.
Esperoct® is a registered trademark of Novo Nordisk Health Care AG.
Novo Nordisk is a registered trademark of Novo Nordisk A/S.
All other trademarks, registered or unregistered, are the property of their respective owners.
© 2025 Novo Nordisk  All rights reserved.  US24ESP00106  March 2025
Novo Nordisk logo.
Novo Nordisk logo.