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Important Safety Information | Prescribing Information
Esperoct antihemophilic factor (recombinant), glycopegylated-exei logo.
Esperoct® is used to treat and prevent or reduce the number of bleeding episodes in people with hemophilia A. See full indication below.
 
Important Safety Information | Prescribing Information
Novoeight Antihemophilic Factor (Recombinant) logo.
Novoeight® is used to control and prevent bleeding in people with hemophilia A. See full indication below.
You are so much more than a "carrier."
Your on-the-go lifestyle helps make you, you. You deserve treatment that can keep up.
 
 
Tammy has hemophilia A and uses Esperoct®
If you are experiencing bleeding symptoms, it’s time for you and your doctor to talk about it. Ask about Esperoct® or Novoeight®: Flexxibility factor therapies designed around your lifestyle
If you are experiencing bleeding symptoms, it’s time for you and your doctor to talk about it. Ask about Esperoct® or Novoeight®: Flexxibility factor therapies designed around your lifestyle
Purse 1 Esperoct®
 
Esperoct® offers proven bleed protection as a flexible extended half-life (EHL) Factor 8 treatment that fits into your lifestyle.a
 
Purse 2 Novoeight®
 
Novoeight® is a standard half-life (SHL) Factor 8 treatment that offers proven bleed control and is designed to go with you.a
 Explore more 
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With Esperoct® and Novoeight®, you can get the reliable bleed protection you deserve:
97%   In a clinical trial of Esperoct®, 97% of all bleeds were controlled with 1 to 2 dosesb
89%   In a clinical trial of Novoeight®, 89% of all bleeds were controlled with 1 to 2 dosesc
aPrior to reconstitution, Esperoct® and Novoeight® can be stored from 36 °F to 46 °F for up to 30 months, at room temperature up to 86 °F for up to 12 months, or up to 104 °F for up to 3 months. See Prescribing Information for complete product storage information.
bData shown are from a study where 12 adult and adolescent previously treated male patients with severe hemophilia chose to be treated on demand and received Esperoct® for 532 bleeding episodes.
cData shown from a study in 150 male patients (aged 12 to 65 years) with severe hemophilia A who received Novoeight® prophylaxis and were treated with additional doses of Novoeight® for 499 breakthrough bleeds.
Keep scrolling to learn more about sharing symptoms with your doctor
Selected Important Safety Information for Novoeight® and Esperoct®
Who should not use Novoeight® or Esperoct®?
  • You should not use Novoeight® or Esperoct® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or Esperoct® or if you are allergic to hamster proteins
What is the most important information I need to know about Novoeight® and Esperoct®?
  • Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia center
  • Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, light-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands
 
Track your symptoms and share with your doctor
When talking to your doctor about treatment options, it is important to share documentation about your bleeds. Use Your Guide to Self-Advocacy to help you record any pain, swelling, bruising, and bleeding you experience so you can advocate for a personalized treatment plan. Taking pictures and videos can also help!
 Get more tips 
 
  Photo of two RBCLs, Kendra and Lorie, standing side by side
Looking for resources or people who understand the unique challenges you face?
There’s an entire community dedicated to supporting women and girls living with hemophilia.
Connect with a Rare Blood Community Liaison (RBCL) to find local events, get personalized support, and learn more about treatment options like Esperoct® and Novoeight®.
 Find your RBCL 
What is Novoeight® and Esperoct®?
Novoeight® (antihemophilic factor, recombinant) and Esperoct® [antihemophilic factor (recombinant), glycopegylated-exei] are injectable medicines used to treat, control, and prevent or reduce the number of bleeding episodes in people with hemophilia A. Your healthcare provider may give you Novoeight® or Esperoct® when you have surgery
  • Novoeight® and Esperoct® are not used to treat von Willebrand Disease
Important Safety Information (cont'd)
What should I tell my healthcare provider before using Novoeight® or Esperoct®?
  • Before taking Novoeight® or Esperoct®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII 
  • Your body can make antibodies called “inhibitors” against Novoeight® or Esperoct®, which may stop Novoeight® or Esperoct® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Novoeight® or Esperoct®
What are the possible side effects of Novoeight® and Esperoct®?
  • Novoeight®: Common side effects of Novoeight® include inhibitors in patients who were not previously treated with factor VIII products, swelling or itching at the location of injection, and fever
  • Esperoct®: Common side effects of Esperoct® include rash or itching, and swelling, pain, rash or redness at the location of infusion
Please click here for Prescribing Information for Novoeight®.
Please click here for Prescribing Information for Esperoct®.
Novoeight® and Esperoct® are prescription medications.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
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Esperoct® and Novoeight® are registered trademarks of Novo Nordisk Health Care AG.
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