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Important Safety Information  |  Prescribing Information
Rebinyn Coagulation Factor IX (Recombinant), GlycoPEGylated logo.
Used to treat, prevent, or reduce the number of bleeding episodes in people with hemophilia B.
See full indication below.
Get personal support from someone you can trust.
 
Hi [First name],
I'm Ajie, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Ajie
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“I wanted to be a liaison for the hemophilia community to help people and keep them connected.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Ajie
Photo of Ajie
“I wanted to be a liaison for the hemophilia community to help people and keep them connected.”
 
Hi [First name],
I'm Brittany, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Brittany
Photo of Brittany
“Hearing people’s stories of overcoming struggle is really what made me interested in working with the hemophilia community.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Brittany
Photo of Brittany
“Hearing people’s stories of overcoming struggle is really what made me interested in working with the hemophilia community.”
 
Hi [First name],
I'm Craig, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Craig
Photo of Craig
“My favorite thing about the hemophilia community is how close and tight-knit it is. There’s a lot of love and people are committed to helping each other.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Craig
Photo of Craig
“My favorite thing about the hemophilia community is how close and tight-knit it is. There’s a lot of love and people are committed to helping each other.”
 
Hi [First name],
I'm Dan, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Dan
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“I make a choice every day to be grateful and make the most of right now, which is all I have guaranteed.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Dan
Photo of Dan
“I make a choice every day to be grateful and make the most of right now, which is all I have guaranteed.”
 
Hi [First name],
I'm Judy, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Judy
Photo of Judy
“I love how the hemophilia community has the passion to get things done, and they don’t let things stand in their way.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Judy
Photo of Judy
“I love how the hemophilia community has the passion to get things done, and they don’t let things stand in their way.”
 
Hi [First name],
I'm Lorie, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Lorie
Photo of Lorie
“After taking care of my son with a severe bleeding disorder, I want to be a resource and lifeline to other families like mine.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Lorie
Photo of Lorie
“After taking care of my son with a severe bleeding disorder, I want to be a resource and lifeline to other families like mine.”
 
Hi [First name],
I'm Michelle, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Michelle
Photo of Michelle
“My favorite thing about the bleeding disorders community is our ability to face obstacles together and grow from them.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Michelle
Photo of Michelle
“My favorite thing about the bleeding disorders community is our ability to face obstacles together and grow from them.”
 
Hi [First name],
I'm Natalie, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Natalie
Photo of Natalie
“My favorite thing about this community is the passion and dedication of its members. They’re always willing to help each other live better with a bleeding disorder.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Natalie
Photo of Natalie
“My favorite thing about this community is the passion and dedication of its members. They’re always willing to help each other live better with a bleeding disorder.”
 
Hi [First name],
I'm Norberto, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Norberto
Photo of Norberto
“My favorite thing about the bleeding disorders community is that they’re one big family whenever they’re together.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Norberto
Photo of Norberto
“My favorite thing about the bleeding disorders community is that they’re one big family whenever they’re together.”
 
Hi [First name],
I'm Sarah, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Sarah
Photo of Sarah
“The commitment and passion within the bleeding disorders community is like nothing I’ve ever seen before.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Sarah
Photo of Sarah
“The commitment and passion within the bleeding disorders community is like nothing I’ve ever seen before.”
 
Hi [First name],
I'm Stacey, your local Hemophilia Community Liaison.
I'm here to support people with bleeding disorders and their caregivers. I can help answer your questions and provide information on treatment options and free trial prescriptions.a
Connect with me today, and we can set up a video, phone or in-person meeting.
Your Hemophilia Community Liaison is:
Stacey
Photo of Stacey
“I’m inspired every day by how close-knit and supportive the bleeding disorders community is.”
 Connect with Me 
Your Hemophilia Community Liaison is:
Stacey
Photo of Stacey
“I’m inspired every day by how close-knit and supportive the bleeding disorders community is.”
 
Hi [First name],
We’re Ajie and Stacey, Hemophilia Community Liaisons.
Our job is to support individuals with bleeding disorders and their caregivers. We can answer questions, provide information on treatment options, and help people get trial prescriptions.a
Best of all, we’re here to lend a helping hand, voice support, and share a listening ear. Please get in touch to meet your local Hemophilia Community Liaison!
Hemophilia Community Liaisons
Ajie & Stacey
Photo of Hemophilia Community Liaisons
“We’re available by e-mail, phone, or video call—whichever is more convenient for you.”
 Connect with Us 
Hemophilia Community Liaisons
Ajie & Stacey
Photo of Hemophilia Community Liaisons
“We’re available by e-mail, phone, or video call—whichever is more convenient for you.”
aPatients who have been prescribed a Novo Nordisk hemophilia and rare bleeding disorder product for an FDA-approved indication, and who have commercial insurance or who are uninsured, may be eligible to receive a limited supply of free product. Patients who participate in any government, state, or federally funded medical or prescription benefit program, including Medicare, Medicaid, Medigap, VA, DOD, and TRICARE, including patients who participate in a managed Medicaid program or have Medicaid as secondary insurance, are not eligible to receive product support. Product is provided at no cost to the patient or the HCP, is not contingent on any product purchase, and the patient and HCP must not: (1) bill any third party for the free product, or (2) resell the free product.
Scroll to learn more about the support we provide.
Selected Important Safety Information
What is the most important information I need to know about Rebinyn®?
• Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.
Who should not use Rebinyn®?
Do not use Rebinyn® if you:
• are allergic to Factor IX or any of the other ingredients of Rebinyn®.
• are allergic to hamster proteins.
Please click here or scroll below for additional Important Safety Information.
Empower yourself with resources.
We’ve got lots of information and tools available to help you manage your hemophilia B. Instructional videos, educational resources, patient stories, and more are at your fingertips.
 See Hemophilia B Resources 
Find more ways to get support.
NovoCare® provides personalized patient support. Learn about our product assistance plans, like our free Trial Prescriptionb and Co-pay Assistancec programs.
 Get Product Support 
bPatients who have been prescribed a Novo Nordisk hemophilia and rare bleeding disorder product for an FDA-approved indication, and who have commercial insurance or who are uninsured, may be eligible to receive a limited supply of free product. Patients who participate in any government, state, or federally funded medical or prescription benefit program, including Medicare, Medicaid, Medigap, VA, DOD, and TRICARE, including patients who participate in a managed Medicaid program or have Medicaid as secondary insurance, are not eligible to receive product support. Product is provided at no cost to the patient or the HCP, is not contingent on any product purchase, and the patient and HCP must not: (1) bill any third party for the free product, or (2) resell the free product.
cNovo Nordisk Hemophilia and Rare Bleeding Disorders Copay/Coinsurance Terms and Conditions: Enrolled patients are eligible for up to $12,000 in co-pay/coinsurance assistance per calendar year for each NNI hemophilia or rare bleeding disorder product. Assistance is retroactive to 60 days. Patients must be commercially insured and may not be participating in any government, state, or federally funded medical or prescription benefit programs, including Medicare, Medicaid, Medigap, VA, DOD, and TRICARE, including patients who participate in a managed Medicaid program or have Medicaid as secondary insurance. Uninsured, cash-paying patients are not eligible to participate. Patients are eligible to receive co-pay/coinsurance assistance on an annual basis (12 months). Offer good only in the USA, Puerto Rico, Guam, Saipan, and Virgin Islands with participating pharmacies and cannot be redeemed at government-subsidized clinics. Void where taxed, restricted, or prohibited by law. Absent a change in Massachusetts law, effective July 1, 2019, the Savings Card will no longer be valid for residents of Massachusetts. Patient is responsible for complying with any insurance carrier co-payment disclosure requirements, including disclosing any savings received from this program. Re-confirmation of information may be requested periodically to ensure accuracy of data and compliance with terms. This is not an insurance program. Novo Nordisk reserves the right to rescind, revoke, or amend this offer without notice at any time. Non-medication expenses, such as ancillary supplies or administration-related costs, are not eligible. Must have a current prescription for an FDA-approved indication.
Indications and Usage
What is Rebinyn®, Coagulation Factor IX (Recombinant), GlycoPEGylated?
Rebinyn® is an injectable medicine used to replace clotting Factor IX that is missing in patients with hemophilia B. Rebinyn® is used to treat, prevent, or reduce the frequency (number) of bleeding episodes in people with hemophilia B. Your healthcare provider may give you Rebinyn® when you have surgery. Rebinyn® is not used for immune tolerance therapy.
Important Safety Information
What is the most important information I need to know about Rebinyn®?
• Do not attempt to do an infusion yourself unless you have been taught how by your healthcare provider or hemophilia treatment center. Carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Rebinyn®.
Who should not use Rebinyn®?
Do not use Rebinyn® if you:
• are allergic to Factor IX or any of the other ingredients of Rebinyn®.
• are allergic to hamster proteins.
What should I tell my healthcare provider before using Rebinyn®?
Tell your healthcare provider if you:
• have or have had any medical conditions.
• take any medicines, including non-prescription medicines and dietary supplements.
• are nursing, pregnant, or plan to become pregnant.
• have been told you have inhibitors to Factor IX.
How should I use Rebinyn®?
• Rebinyn® is given as an infusion into the vein.
• Call your healthcare provider right away if your bleeding does not stop after taking Rebinyn®.
• Do not stop using Rebinyn® without consulting your healthcare provider.
What are the possible side effects of Rebinyn®?
• Common side effects include infusion site reaction (bruising, bleeding, swelling, pain, or redness), itching, and rash.
• Your body can also make antibodies called “inhibitors” against Factor IX, including Rebinyn®, which may stop Rebinyn® from working properly. Your healthcare provider may need to test your blood for inhibitors from time to time.
• Call your healthcare provider right away or get emergency treatment right away if you get, for example, any of the following signs of an allergic reaction: hives, chest tightness, wheezing, difficulty breathing, and/or swelling of the face.
• You may be at an increased risk of forming blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider if you have chest pain, difficulty breathing, leg tenderness, or swelling.
• Animals given repeat doses of Rebinyn® showed Polyethylene Glycol (PEG) in certain cells in the brain. The potential human implications of these animal tests are unknown.
Please click here for Prescribing Information.
Rebinyn® is a prescription medication.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please do not respond to this email. If you would like to contact us, please click here or call 1‑877‑744‑2579.
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Rebinyn® is a registered trademark and NovoCare® is a trademark of Novo Nordisk A/S.
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© 2023 Novo Nordisk  All rights reserved.  US22REB00199  February 2023
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