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Scientists are researching different approaches to the coagulation cascade.

Different approaches to the coagulation cascade

Scientists are researching alternative approaches to coagulation. These include:

	•	Hemostasis by anticoagulant inhibition vs procoagulant addition
	•	Substitution therapies like factor mimetics
	•	Gene therapy

Learn about the alternative approaches being studied and get to know the coagulation cascade in a new video.

Explore coagulation approaches

Patients’ most common burdens

A new survey reveals what hemophilia patients reported as their most common physical, mental, and emotional burdens.

See the data

Different administration options are being researched, too

Patients express concerns and burdens associated with administration, so scientists are investigating different approaches to the administration of hemophilia therapy.^1-4

Rethink administration

Stay in the know

Keep up to date with the latest in hemophilia research.

References:

1.	Wiley RE, Khoury CP, Snihur AWK, et al. From the voices of people with haemophilia A and their caregivers: Challenges with current treatment, their impact on quality of life and desired improvements in future therapies. Haemophilia. 2019;25(3):433-440.
2.	Srivastava A, Santagostino E, Dougall A, et al. WFH Guidelines for the Management of Hemophilia, 3rd edition [published correction appears in Haemophilia. 2021 Jul;27(4):699]. Haemophilia. 2020;26 Suppl 6:1-158.
3.	Fifer S, Kerr AM, Parken C, Hamrosi K, Eid S. Treatment preferences in people with haemophilia A or caregivers of people with haemophilia A: a discrete choice experiment. Haemophilia. 2020;26 Suppl 5:30-40.
4.	Park YS, Hwang TJ, Cho GJ, et al. Patients' and parents' satisfaction with, and preference for, haemophilia A treatments: a cross-sectional, multicentre, observational study. Haemophilia. 2021;27(4):563-573.

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